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Hair Pipeline

What changed

Every verified phase change across the register, newest first. This is the page to bookmark.

Only human-verified changes appear here.

August 20261 change

  1. VC005moved toPhase 2

    First Phase 2 trial on record: NCT07749716 — Phase II Clinical Study of VC005 Tablets in Subjects With Severe Alopecia Areata

    ClinicalTrials.gov ↗

July 20262 changes

  1. Upadacitinib (Rinvoq)moved toApproved

    Approved by the European Commission for severe alopecia areata in adults and adolescents from 12. Still under FDA review in the US.

    Company release ↗
  2. APSMNFmoved toPhase 3

    First Phase 3 trial on record: NCT07516561 — Efficacy and Safety of APSMNF in the Treatment of Male Androgenetic Alopecia

    ClinicalTrials.gov ↗

April 20262 changes

  1. LY4005130moved toPhase 2

    First Phase 2 trial on record: NCT07533006 — A Study of LY4005130 in Adult Participants With Severe Alopecia Areata (Hair Loss)

    ClinicalTrials.gov ↗
  2. TH07moved toPhase 3

    First Phase 3 trial on record: NCT07435012 — Androgenic Alopecia TH07 Clinical Trial

    ClinicalTrials.gov ↗

January 20261 change

  1. Registered on ClinicalTrials.gov as NCT07618195: Study of EPI-001 in Patients With Androgenetic Alopecia

    ClinicalTrials.gov ↗

December 20253 changes

  1. LAD603moved toPhase 2

    First Phase 2 trial on record: NCT07311564 — A Study of LAD603 in Adults With Alopecia Areata

    ClinicalTrials.gov ↗
  2. OLX104C (OLX72021)moved toPhase 1/2

    First Phase 1/2 trial on record: NCT07327359 — A Study to Evaluate Safety and Efficacy of OLX72021 in Healthy Males With Androgenetic Alopecia

    ClinicalTrials.gov ↗
  3. ABS-201moved toPhase 1/2

    First Phase 1/2 trial on record: NCT07317544 — Study of ABS-201 Evaluating Single and Multiple Ascending Doses in Adults With and Without Androgenetic Alopecia

    ClinicalTrials.gov ↗

May 20252 changes

  1. SYHX1901moved toPhase 2

    First Phase 2 trial on record: NCT06562894 — Study to Evaluate Safety and Efficacy of SYHX1901 Tablets in Severe Alopecia Areata Patients

    ClinicalTrials.gov ↗
  2. PDFE-2304 (Neopili)moved toPhase 2

    First Phase 2 trial on record: NCT07011485 — A Safety and Efficacy Study of PDFE-2304 Topical Solution for the Treatment of Androgenic Alopecia.

    ClinicalTrials.gov ↗

April 20251 change

  1. CKD-843moved toPhase 3

    First Phase 3 trial on record: NCT06916793 — A Phase 3 Study to Evaluate the Safety and Efficacy of CKD-843 in Male Patients With Androgenetic Alopecia

    ClinicalTrials.gov ↗

March 20252 changes

  1. ALD-102moved toPhase 1/2

    First Phase 1/2 trial on record: NCT06826196 — A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ALD-102 Solution in Subjects With Alopecia Areata

    ClinicalTrials.gov ↗
  2. First Phase 3 trial on record: NCT06972264 — Safety and Efficacy of VDPHL01 in Males With AGA

    ClinicalTrials.gov ↗

January 20252 changes

  1. First Phase 3 trial on record: NCT06501924 — Clinical Study of DA-002 and DA-005 As a Treatment for Hair Loss

    ClinicalTrials.gov ↗
  2. OMA102moved toPhase 3

    First Phase 3 trial on record: NCT05824065 — Efficacy and Safety of OMA102 in the Treatment of Female Pattern Hair Loss

    ClinicalTrials.gov ↗

November 20241 change

  1. VDPHL-01 (oral minoxidil)moved toPhase 2/3

    First Phase 2/3 trial on record: NCT06724614 — Efficacy and Safety of VDPHL01 in Males With AGA

    ClinicalTrials.gov ↗

October 20241 change

  1. First Phase 3 trial on record: NCT05888922 — Evaluation of Efficacy and Safety of Oral Minoxidil 1 mg in Female Androgenetic Alopecia

    ClinicalTrials.gov ↗

September 20241 change

  1. NXC736moved toPhase 2

    First Phase 2 trial on record: NCT06104839 — Safety and Efficacy of Oral NXC-736 in Adult Participants With Moderate and Severe Alopecia Areata

    ClinicalTrials.gov ↗

July 20241 change

  1. First Phase 2 trial on record: NCT06527365 — Safety and Efficacy of VDPHL01 in Males and Females With AGA

    ClinicalTrials.gov ↗

June 20242 changes

  1. Amlitelimabmoved toPhase 2

    First Phase 2 trial on record: NCT06444451 — A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

    ClinicalTrials.gov ↗
  2. PP405moved toPhase 2

    First Phase 2 trial on record: NCT06393452 — Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA

    ClinicalTrials.gov ↗

April 20242 changes

  1. Baricitinib (Olumiant)moved toApproved

    First APPROVED trial on record: NCT06240351 — A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)

    ClinicalTrials.gov ↗
  2. First Phase 2 trial on record: NCT06340360 — A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

    ClinicalTrials.gov ↗

October 20231 change

  1. Upadacitinib (Rinvoq)moved toPhase 3

    First Phase 3 trial on record: NCT06012240 — A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

    ClinicalTrials.gov ↗

September 20233 changes

  1. Olevaprubart (IMG-007)moved toPhase 1/2

    First Phase 1/2 trial on record: NCT06060977 — A Study to Evaluate the Safety, Pharmacokinetics and Efficacy of IMG-007 in Adult Alopecia Areata Participants

    ClinicalTrials.gov ↗
  2. Bempikibart (ADX-914)moved toPhase 2

    First Phase 2 trial on record: NCT06018428 — A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

    ClinicalTrials.gov ↗
  3. HMI-115moved toPhase 2

    First Phase 2 trial on record: NCT06118866 — A Study to Assess the Efficacy and Safety of HMI-115 in Male Subjects With Androgenetic Alopecia

    ClinicalTrials.gov ↗

June 20231 change

  1. First Phase 3 trial on record: NCT05910450 — A Study to Evaluate the Efficacy and Safety of Clascoterone Solution in Treatment of Male Pattern Hair Loss

    ClinicalTrials.gov ↗

April 20232 changes

  1. Farudodstat (ASLAN003)moved toPhase 2

    First Phase 2 trial on record: NCT05865041 — Investigate the Efficacy and Safety of Farudodstat Compared With Its Placebo in Adult Alopecia Areata Participants

    ClinicalTrials.gov ↗
  2. GT20029moved toPhase 2

    First Phase 2 trial on record: NCT06692465 — To Evaluate the Efficacy and Safety of GT20029 Solution in the Treatment of Androgenetic Alopecia (AGA) in Chinese Adult Males

    ClinicalTrials.gov ↗

March 20232 changes

  1. First Phase 2 trial on record: NCT05778825 — A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors

    ClinicalTrials.gov ↗
  2. TDM-105795moved toPhase 2

    First Phase 2 trial on record: NCT05802173 — Study of TDM-105795 Following Topical Administration in Male Subjects With Androgenetic Alopecia

    ClinicalTrials.gov ↗

January 20231 change

  1. BL 3000moved toPhase 3

    First Phase 3 trial on record: NCT04880889 — BL3000 Compared to Pantogar® in the Treatment of Telogen Effluvium in Women.

    ClinicalTrials.gov ↗

December 20222 changes

  1. CKD-498moved toPhase 2

    First Phase 2 trial on record: NCT05677438 — A Phase 2 Study to Evaluate the Safety and Efficacy of CKD-498 in Female Patients With Androgenetic Alopecia

    ClinicalTrials.gov ↗
  2. DLQ-01 (latanoprost)moved toPhase 1/2

    First Phase 1/2 trial on record: NCT05636904 — Safety and Efficacy Study of Topical DLQ01 in the Treatment of Androgenetic Alopecia (AGA) in Men

    ClinicalTrials.gov ↗

November 20222 changes

  1. KL130008moved toPhase 2

    First Phase 2 trial on record: NCT05496426 — A Study of KL130008 in Adults With Severe Alopecia Areata

    ClinicalTrials.gov ↗
  2. Deucravacitinibmoved toPhase 2

    First Phase 2 trial on record: NCT05556265 — A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia Areata

    ClinicalTrials.gov ↗

September 20221 change

  1. First Phase 2 trial on record: NCT04011748 — Clinical Application of Stem Cell Educator Therapy in Alopecia Areata

    ClinicalTrials.gov ↗

May 20221 change

  1. HMI-115moved toPhase 1

    First Phase 1 trial on record: NCT05324293 — To Evaluate the Safety, Tolerability and Efficacy in Male and Female with AGA Treated with HMI-115 Over a 24-week Treatment Period

    ClinicalTrials.gov ↗

April 20222 changes

  1. Daxdilimabmoved toPhase 2

    First Phase 2 trial on record: NCT05368103 — Study of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia Areata

    ClinicalTrials.gov ↗
  2. First Phase 3 trial on record: NCT05470413 — Evaluate the Efficacy and Safety of SHR0302 in Adult Patients With Severe Alopecia Areata

    ClinicalTrials.gov ↗

March 20221 change

  1. STS01moved toPhase 2

    First Phase 2 trial on record: NCT06402630 — A Phase 2 Placebo Controlled, Clinical Trial Designed to Assess the Efficacy, Safety and Dose Response Characterisation of STS01 for the Treatment of Mild-moderate Alopecia Areata (AA)

    ClinicalTrials.gov ↗

December 20212 changes

  1. Pyrilutamidemoved toPhase 3

    First Phase 3 trial on record: NCT06126965 — Phase III Study of KX-826 With Adult Male Patients With AGA

    ClinicalTrials.gov ↗
  2. Rosnilimabmoved toPhase 2

    First Phase 2 trial on record: NCT05205070 — A Study to Evaluate the Efficacy and Safety of Rosnilimab (ANB030) in Treatment of Subjects With Moderate-to-Severe Alopecia Areata

    ClinicalTrials.gov ↗

October 20211 change

  1. EQ101 (BNZ-1)moved toPhase 2

    First Phase 2 trial on record: NCT03532958 — Phase 2 Trial of BNZ-1 in Patients With Moderate to Severe Alopecia Areata

    ClinicalTrials.gov ↗

September 20212 changes

  1. IVL3001moved toPhase 1/2

    First Phase 1/2 trial on record: NCT04945226 — A Clinical Trial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of IVL3001

    ClinicalTrials.gov ↗
  2. Jaktinibmoved toPhase 3

    First Phase 3 trial on record: NCT05051761 — Study to Evaluate the Safety and Efficacy of Jaktinib in Adults With Alopecia Areata

    ClinicalTrials.gov ↗

July 20211 change

  1. GT20029moved toPhase 1

    First Phase 1 trial on record: NCT06468579 — To Evaluate the Safety, Tolerability and PK of GT20029 Gel and Solution in Healthy Subjects

    ClinicalTrials.gov ↗

June 20211 change

  1. First Phase 3 trial on record: NCT04825561 — A Study to Evaluate the Efficacy and Safety of AD-208

    ClinicalTrials.gov ↗

April 20212 changes

  1. CKD-843moved toPhase 1

    First Phase 1 trial on record: NCT04805606 — A Clinical Traial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of CKD-843

    ClinicalTrials.gov ↗
  2. TDM-105795moved toPhase 1

    First Phase 1 trial on record: NCT04913519 — A Phase 1 Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA)

    ClinicalTrials.gov ↗

November 20201 change

  1. First Phase 3 trial on record: NCT04518995 — Study to Evaluate the Efficacy and Safety of CTP-543 in Adults With Moderate to Severe Alopecia Areata (THRIVE-AA1)

    ClinicalTrials.gov ↗

September 20201 change

  1. Pyrilutamidemoved toPhase 2

    First Phase 2 trial on record: NCT05940506 — Phase II Study Evaluating the Efficacy and Safety of KX-826

    ClinicalTrials.gov ↗

July 20201 change

  1. Etrasimodmoved toPhase 2

    First Phase 2 trial on record: NCT04556734 — Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata

    ClinicalTrials.gov ↗

May 20201 change

  1. First Phase 2 trial on record: NCT04346316 — A Phase II Study in Patients With Alopecia Areata

    ClinicalTrials.gov ↗

January 20201 change

  1. First Phase 1 trial on record: NCT04214808 — To Evaluate the Pharmacokinetics and Safety of AD-208

    ClinicalTrials.gov ↗

November 20191 change

  1. Jaktinibmoved toPhase 2

    First Phase 2 trial on record: NCT04034134 — Study to Evaluate the Safety and Efficacy ofJaktinib Hydrochloride Tablets in Severe Alopecia Areata

    ClinicalTrials.gov ↗

July 20192 changes

  1. Ritlecitinib (Litfulo)moved toPhase 3

    First Phase 3 trial on record: NCT04006457 — Long-Term PF-06651600 for the Treatment of Alopecia Areata

    ClinicalTrials.gov ↗
  2. Baricitinib (Olumiant)moved toPhase 3

    First Phase 3 trial on record: NCT03899259 — A Study of Baricitinib (LY3009104) in Adults With Severe or Very Severe Alopecia Areata

    ClinicalTrials.gov ↗

April 20191 change

  1. Deuruxolitinib (Leqselvi)moved toPhase 2/3

    First Phase 2/3 trial on record: NCT03898479 — Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata

    ClinicalTrials.gov ↗

January 20191 change

  1. Pyrilutamidemoved toPhase 1

    First Phase 1 trial on record: NCT04984707 — Safety, Tolerability and Pharmacokinetics of KX826 in Healthy Male Subjects With Androgenetic Alopecia Following Topical Single Ascending Dose Administration

    ClinicalTrials.gov ↗

December 20181 change

  1. Ritlecitinib (Litfulo)moved toPhase 2/3

    First Phase 2/3 trial on record: NCT03732807 — PF-06651600 for the Treatment of Alopecia Areata

    ClinicalTrials.gov ↗

November 20181 change

  1. Dalosirvat (SM-04554)moved toPhase 2/3

    First Phase 2/3 trial on record: NCT03742518 — A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia

    ClinicalTrials.gov ↗

September 20181 change

  1. Baricitinib (Olumiant)moved toPhase 2/3

    First Phase 2/3 trial on record: NCT03570749 — A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata

    ClinicalTrials.gov ↗

June 20181 change

  1. ATI-501moved toPhase 2

    First Phase 2 trial on record: NCT03594227 — ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

    ClinicalTrials.gov ↗

May 20181 change

  1. ENERGI-F701moved toPhase 2

    First Phase 2 trial on record: NCT03351322 — ENERGI-F701 for Female Hair Loss Treatment

    ClinicalTrials.gov ↗

February 20181 change

  1. FOL-005moved toPhase 2

    First Phase 2 trial on record: NCT03467412 — To Investigate Efficacy of FOL-005 on Hair Growth on Scalp Skin

    ClinicalTrials.gov ↗

November 20171 change

  1. ATI-50002moved toPhase 2

    First Phase 2 trial on record: NCT03354637 — A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata

    ClinicalTrials.gov ↗

August 20171 change

  1. First Phase 2 trial on record: NCT03137381 — Study to Evaluate the Safety and Efficacy of CTP-543 in Adults With Moderate to Severe Alopecia Areata

    ClinicalTrials.gov ↗

February 20171 change

  1. First Phase 2 trial on record: NCT02636244 — Safety and Efficacy Study of SHAPE Gel in Alopecia Areata

    ClinicalTrials.gov ↗

December 20162 changes

  1. Ritlecitinib (Litfulo)moved toPhase 2

    First Phase 2 trial on record: NCT02974868 — Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata

    ClinicalTrials.gov ↗
  2. Brepocitinibmoved toPhase 2

    First Phase 2 trial on record: NCT02974868 — Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata

    ClinicalTrials.gov ↗

October 20161 change

  1. CG 428moved toPhase 2

    First Phase 2 trial on record: NCT02919735 — Efficacy, Safety and Tolerability of CG428 Cutaneous Solution on Chemotherapy Induced Alopecia; Controlled Study (ELAN)

    ClinicalTrials.gov ↗

August 20161 change

  1. Topical finasteridemoved toPhase 3

    First Phase 3 trial on record: NCT03004469 — Study to Evaluate the Efficacy and Safety of P-3074 Topical Solution in the Treatment of Androgenetic Alopecia

    ClinicalTrials.gov ↗

July 20161 change

  1. Setipiprantmoved toPhase 2

    First Phase 2 trial on record: NCT02781311 — A Safety and Efficacy Study of Setipiprant Tablets in Androgenetic Alopecia in Males

    ClinicalTrials.gov ↗

January 20162 changes

  1. FOL-005moved toPhase 1/2

    First Phase 1/2 trial on record: NCT02793557 — Investigation of FOL-005 on Clinical Safety and Effect on Hair Growth

    ClinicalTrials.gov ↗
  2. First Phase 2 trial on record: NCT02561585 — LEO 124249 Ointment in the Treatment of Alopecia Areata

    ClinicalTrials.gov ↗

November 20151 change

  1. First Phase 2 trial on record: NCT02553330 — A Study With Ruxolitinib Phosphate Cream Applied Topically to Subjects With Alopecia Areata (AA)

    ClinicalTrials.gov ↗

November 20141 change

  1. Dalosirvat (SM-04554)moved toPhase 2

    First Phase 2 trial on record: NCT02275351 — A Study of the Safety, Tolerability, and Efficacy of Topical SM04554 Solution in Male Subjects With Androgenetic Alopecia (AGA)

    ClinicalTrials.gov ↗

October 20141 change

  1. First Phase 2 trial on record: NCT02279823 — A Phase 2 Study to Evaluate the Safety and Efficacy of CB-03-01 Solution, a Comparator Solution and Vehicle Solution in Males With Androgenetic Alopecia

    ClinicalTrials.gov ↗

August 20121 change

  1. First Phase 1/2 trial on record: NCT01673789 — Stem Cell Educator Therapy in Alopecia Areata

    ClinicalTrials.gov ↗

December 20111 change

  1. First Phase 1/2 trial on record: NCT01501617 — Safety and Efficacy of Hair Stimulating Complex (HSC) on Hair Growth in Males With Androgenetic Alopecia

    ClinicalTrials.gov ↗

June 20111 change

  1. Bimatoprost (scalp)moved toPhase 2

    First Phase 2 trial on record: NCT01325337 — Safety and Efficacy Study of Bimatoprost in the Treatment of Men With Androgenic Alopecia

    ClinicalTrials.gov ↗

December 20101 change

  1. RCH-01moved toPhase 1/2

    First Phase 1/2 trial on record: NCT01286649 — Safety and Efficacy Study of Human Autologous Hair Follicle Cells to Treat Androgenetic Alopecia

    ClinicalTrials.gov ↗

October 20101 change

  1. Bimatoprost (scalp)moved toPhase 1

    First Phase 1 trial on record: NCT01189279 — Safety and Pharmacokinetics Study of New Formulation of Bimatoprost in Patients With Alopecia

    ClinicalTrials.gov ↗

October 20081 change

  1. First Phase 2 trial on record: NCT01451021 — A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss

    ClinicalTrials.gov ↗

January 20071 change

  1. NEOSH101moved toPhase 2

    First Phase 2 trial on record: NCT00418730 — Efficacy Study of Topical NEOSH101 to Treat Male Pattern Hair Loss

    ClinicalTrials.gov ↗

December 20061 change

  1. First Phase 3 trial on record: NCT00441116 — A Study To Assess The Efficacy And Safety Of Dutasteride 0.5mg Once Daily For 6 Months In The Treatment Of Male Subjects With Androgenetic Alopecia

    ClinicalTrials.gov ↗

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