Alopecia areata
An autoimmune condition in which the immune system attacks the hair follicle, causing patchy or total loss. It is not pattern baldness and does not respond to the same treatments.
This is where the field has moved fastest. Nothing systemic was approved anywhere before June 2022; there are now several JAK inhibitors, and the live question has shifted to what you offer the people they do not work for.
Available today
- Baricitinib (Olumiant)ApprovedEli LillyHigh
- Deuruxolitinib (Leqselvi)ApprovedSun PharmaceuticalHigh
- JaktinibApprovedSuzhou Zelgen BiopharmaceuticalsHigh
- Ritlecitinib (Litfulo)ApprovedPfizerHigh
- Upadacitinib (Rinvoq)ApprovedAbbVieHigh
In development
- Ivarmacitinib (ARQ-252)Filed with regulatorUnknownMedium
- BrepocitinibPhase 2/3Priovant TherapeuticsMedium
- Coacillium (LH-8)Phase 2/3Legacy HealthcareHigh
- Bempikibart (ADX-914)Phase 2Q32 BioHigh
- Delgocitinib (LEO 124249)Phase 2LEO PharmaHigh
- DeucravacitinibPhase 2Bristol Myers SquibbHigh
- LAD603Phase 2AlmirallLow
- LY4005130Phase 2Eli LillyLow
- NXC736Phase 2NEXTGEN BioscienceLow
- Olevaprubart (IMG-007)Phase 2ImageneBioHigh
- Rezpegaldesleukin (REZPEG)Phase 2Nektar TherapeuticsHigh
- STS01Phase 2Soterios PharmaMedium
- SYHX1901Phase 2CSPC Pharmaceutical GroupLow
- VC005Phase 2Jiangsu Vcare PharmaceuticalLow
- ALD-102Phase 1/2Aldena TherapeuticsMedium
Discontinued
Kept deliberately — the history of failures is as informative as the successes.
- DaxdilimabPhase 2AmgenHigh
- EQ101 (BNZ-1)Phase 2EquilliumMedium
- Stem Cell Educator therapyPhase 2Throne BiotechnologiesMedium
- AmlitelimabDiscontinuedSanofiHigh
- ATI-50002DiscontinuedAclaris TherapeuticsMedium
- ATI-501DiscontinuedAclaris TherapeuticsMedium
- EtrasimodDiscontinuedPfizerMedium
- Farudodstat (ASLAN003)DiscontinuedASLAN PharmaceuticalsMedium
- KL130008DiscontinuedKelun-BiotechHigh
- Remetinostat (SHP-141, SHAPE gel)DiscontinuedTetraLogic PharmaceuticalsMedium
- RosnilimabDiscontinuedAnaptysBioHigh
- Ruxolitinib cream (alopecia areata)DiscontinuedIncyteHigh
- Tesnatilimab (JNJ-64304500)DiscontinuedJohnson & JohnsonHigh
Home remedies, checked against the evidence
- Does onion juice regrow hair?
One small 2002 study in alopecia areata, with no repeat we could find. Nothing in pattern baldness.
This page is generated from the register and updates with it. It does not rank treatments by efficacy or announce launch dates — see how we track. A research register, not medical advice: talk to a dermatologist about your own case.