Androgenetic alopecia
The common, gradual, hormone-driven thinning that accounts for most hair loss in men and a large share in women. It is the indication almost every programme in this register is aimed at.
Two drugs have been approved for it for decades and nothing has joined them. What is in development below is mostly trying to do better than those two, not to replace something that failed.
Available today
- Minoxidil (low-dose oral)Marketed, off-labelUnknownHigh
- Dutasteride (Avodart / Zagallo)ApprovedGSKHigh
- Finasteride (Propecia)ApprovedOrganonHigh
- Minoxidil (topical)ApprovedUnknownHigh
- Topical finasterideApprovedAlmirallHigh
In development
- AD-208 (low-dose dutasteride)Phase 3AddpharmaMedium
- APSMNFPhase 3Apsen FarmacêuticaLow
- CKD-843Phase 3Chong Kun Dang PharmaceuticalMedium
- Clascoterone (Breezula)Phase 3Cosmo PharmaceuticalsHigh
- PyrilutamidePhase 3Kintor PharmaceuticalHigh
- TH07Phase 3Triple HairLow
- VDPHL-01 (oral minoxidil)Phase 3VeradermicsMedium
- Dalosirvat (SM-04554)Phase 2/3Biosplice TherapeuticsMedium
- GT20029Phase 2Kintor PharmaceuticalMedium
- HMI-115Phase 2Hope MedicineMedium
- PDFE-2304 (Neopili)Phase 2PDFE Pharma InnovationsLow
- PP405Phase 2Pelage PharmaceuticalsHigh
- TDM-105795Phase 2TechnoDerma MedicinesMedium
- ABS-201Phase 1/2AbsciHigh
- AD-303 (topical dutasteride)Phase 1/2Moogene MediLow
- DA-001 / DA-002 / DA-005Phase 1/2Applied BiologyMedium
- DLQ-01 (latanoprost)Phase 1/2DermaLiq TherapeuticsMedium
- Epibiotech dermal papilla cell therapyPhase 1/2EpibiotechMedium
- IVL3001Phase 1/2Inventage LabMedium
- OLX104C (OLX72021)Phase 1/2Olix PharmaceuticalsMedium
- Xvie (amniotic fluid injectable)Phase 1/2XtresséMedium
- AMP-303Phase 1AmplificaMedium
- ANR-001.1 (latanoprost + minoxidil)Phase 1Aneira PharmaLow
- ET-02Phase 1Eirion TherapeuticsMedium
- HairClone follicle banking & cell therapyPhase 1HairCloneMedium
- OrganTech / Tsuji follicular primordiumPreclinicalOrganTechLow
- TissUse Smart Hair TransplantPreclinicalTissUseLow
Discontinued
Kept deliberately — the history of failures is as informative as the successes.
- FOL-005Phase 2FollicumLow
- RCH-01Phase 2RepliCel Life SciencesMedium
- Aderans dermal sheath cup cells (Ji Gami)DiscontinuedAderans Research InstituteMedium
- ATI-50002DiscontinuedAclaris TherapeuticsMedium
- Bimatoprost (scalp)DiscontinuedAbbVieMedium
- HST-001 (Hair Stimulating Complex)DiscontinuedHistogenHigh
- NEOSH101DiscontinuedNeosilMedium
- SetipiprantDiscontinuedAbbVieHigh
- Stemson Therapeutics hair follicle neogenesisDiscontinuedStemson TherapeuticsMedium
Home remedies, checked against the evidence
- Does rosemary oil regrow hair?
One small 2015 trial against low-strength minoxidil, with no placebo group. It does not show rosemary works as well as minoxidil.
- Does rice water make hair grow?
No study has tested rice water on hair growth. The one study of rice water measured how hair strands feel.
- Does pumpkin seed oil regrow hair?
One placebo-controlled trial, in 76 men, paid for by the company that supplied the capsules, which may have contained more than pumpkin seed oil.
- Does saw palmetto regrow hair?
Small trials, two of them run or backed by companies selling an extract. The one head-to-head comparison found it did less than finasteride.
- Does caffeine shampoo stop hair loss?
The best trial had no placebo and was paid for by Alpecin's maker. The UK advertising regulator ruled Alpecin's hair-loss claim misleading.
- Does biotin help hair loss?
It helps people who lack biotin, which is uncommon. No good trial shows it helps anyone else, and high doses can distort blood tests.
- Does castor oil regrow hair?
We found no study testing castor oil alone on hair growth in people, on the scalp, eyebrows or eyelashes.
- Does peppermint oil regrow hair?
One study, in mice. We found no human trial of peppermint oil on hair growth.
This page is generated from the register and updates with it. It does not rank treatments by efficacy or announce launch dates — see how we track. A research register, not medical advice: talk to a dermatologist about your own case.